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Objective:To clarify the infection and epidemic characteristics of the human metapneumovirus (HMPV) in Chinese patients with febrile respiratory syndrome (FRS), and to provide important baseline data for clinical diagnosis, treatment, prevention and control of HMPV-induced respiratory tract diseases in China.Methods:FRS cases from January 2009 to June 2021 in 9 provinces in China, including Beijing, Hebei, Jilin, Shandong, Shaanxi, Xinjiang, Anhui, Guangdong, Hunan were retrospectively analyzed for their respiratory samples, clinical and epidemic data.The respiratory samples were detected for HMPV by quantitative real-time PCR.Results:A total of 11 660 cases were tested for HMPV, involving 296 (2.54%) HMPV-positive cases.Among 296 HMPV-positive cases, 218 were single HMPV infection, and 78/296 (26.35%) were co-infected with one or more respiratory viruses.HMPV mainly affected children under 5 years of age (3.10%), and in this population, the proportion of pneumonia in HMPV co-infection cases was significantly higher than that of single HMPV infection.HMPV could be detected all year round, which was more popular in winter and spring, with the peak of HMPV epidemic in March.Conclusions:HMPV is one of the important pathogens causing acute respiratory infection in children, showing a clear seasonal epidemic.HMPV can be infected alone or in combination with other respiratory viruses, which may increase the risk of pneumonia in children.
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Objective To evaluate the clinical effect of vertebra pedical nail strengthened by bone cement.Methods 48 cases with vertebral illness were divided into two groups,each group of 24 cases.One group goes ahead of the restvertebra pedical nail dishpour into viscous polymethyl methacrylate(PMMA),another group fixed by regular vertebra pedical nail.VAS score,spinal stability and JOA score were adopted to evaluate curative effect synthetically.Results After 1 month,6 months,12 months,the VAS scores in the treatment group were(3.12 ± 1.65),(3.08 ±1.10),(3.09 ± 1.25),and the VAS scores in the control group were(4.31 ±2.13),(4.22 ± 1.48),(4.12 ±1.34),the VAS scores had statistically significant differences between the two groups postoperative 1 month,6months,12 months(t =2.15,2.08,1.97,all P＜0.05);after 1 month,6 months,12 months JOA scores in the treatment group were(26.76 ±4.36),(26.78 ±2.10),(26.96 ± 1.89),and JOA scores in the control group were (24.13 ± 5.28),(24.32 ± 1.68),(24.32 ± 1.99),the JOA score differences had statistically significances between the two groups(x2 =5.031,P ＜0.05);the excellent rates of the treatment group was 90.13％,which was higher than 85.01％ of the control group(t =3.54,3.39,3.56,all P ＜ 0.05).Conclusion Patients receiving vertebra pedical nail strengthened by bone cement was better than regular vertebra pedical nail skill.